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The Synthesis of 5'-Deoxy-5'-S-(3-methylthiopropylamine)sulfoniumadenosine (“Decarboxylated S-Adenosylmethionine”)

✍ Scribed by Jamieson, G. A.


Book ID
126320580
Publisher
American Chemical Society
Year
1963
Tongue
English
Weight
566 KB
Volume
28
Category
Article
ISSN
0022-3263

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In order to separate S-adenosyl-(5')-3-methylthiopropylamine (decarboxylated AdoMet) from its biological precursor, S-adenosylmethionine (AdoMet), two procedures have been devised. The first method involves two sequential chromatographic steps on Dowex 50, H+ form, and Dowex 1, OH-form, respectively