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Synthesis of 3′-deoxy-5′-S-ethyl-5′-thio-β-d-erythro-pentofuranosylthymine as potential antitumor agent

✍ Scribed by Najim A. Al-Masoudi

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
114 KB
Volume
40
Category
Article
ISSN
0040-4039

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Synthesis and Antiviral Activities of 5-Substituted 1-(2-Deoxy-2-C-methylene-4-thio-β-D-erythro-pentofuranosyl) uracils. -A variety of the title nucleosides [cf. (VII)/(VIII), (X)] are prepared using sila-Pummerer-type glycosylation as key step. The majority of the β-anomers of these nucleosides po