The synthesis of 3β, 11β-dihydroxy-5-androsten-17-one, 5-pregnene-3β, 11β, 17α, 20α-tetrol and 5-pregnene-3β, 11β, 17α, 20β-tetrol tritiated at C-1
✍ Scribed by G. Halperin; J. Weidenfeld
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- French
- Weight
- 169 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
3p-hydroxy-ateroidm, i a deacribed: 3p, 1 1 p-di hydroxy-5-androaten-17-one, 5-pregnene-3ps 1lP,17ab2Oa-tetrol and 5-preqnene-3p,1lps 17a , top-tetrol.
📜 SIMILAR VOLUMES
## Abstract In order to fully understand the metabolic transformations of adrenocortical steroids, labelled 3α, 11β 17α,211‐tetrahydroxy‐5α‐pregnan‐20‐one, Reichstein's Compound C was required. Starting from hydrocortisone, the synthesis of [1−^3^H]‐Reichstein's Compound C has been accomplished.
## Abstract A convenient synthesis of 5α‐[20β‐^2^H]pregnane‐3α,20α‐diol and 5α‐[20β‐^2^H]pregnane‐3β,20α‐diol from 3β‐hydroxy‐5α‐pregn‐16‐en‐20‐one is described. The reaction products are characterized by combined gas chromatography‐mass spectrometry.