✍ Scribed by P.P.M. Bonsen; G.H. de Haas; L.L.M. van Deenen
No coin nor oath required. For personal study only.
The synthesis of 1-oleoyl-2-palmitoyl glycerol-3-phosphoryl-l'-glycerol is described. By means of a reaction between a 1.2-diacyl-glycerol iodohydrin and the silver salt of 2.3isopropylidene glycerol-l-(benzyl)-phosphate and removal of the protecting groups phosphatidyl glycerol was obtained in the same stereochemical configuration as the naturally occurring substance. Confirmation of the structure of the synthesized compound was achieved with the aid of different enzymes and analytical procedures.
📜 SIMILAR VOLUMES
The synthesis of phosphatldylethanolamlne is described The method m~olves a condensahon of d~palmltoylglycerolphosphate with N-ter butyloxycarbon}lethanolamlne m the presence of dJcyclohexylcarbodllmlde After removal of the N-blocking group, the final product is purified by Sephadex LH-20 column chr
The lungs of fetuses of streptozotocin-diabetic rats were examined for their ability to incorporate U-14C-glucose into phosphatidyl choline, phosphatidyl glycerol, phosphatidyl inositol and lysophosphatidyl choline. In the lungs of control rats an increased biosynthesis of phosphatidyl glycerol in l