The synthesis of 2,3-dihydro-4(1H)-quinazolinone angiotensin II receptor antagonists
โ Scribed by Jeremy I. Levin; Peter S. Chan; Trina Bailey; Andrew S. Katocs Jr.; A.M. Venkatesan
- Book ID
- 108476884
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 338 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The solid-phase synthesis of 3,4-dihydro-2(1H)-quinazolinones and 3,4-dihydro-1H-quinazolin-2-thiones is described. Starting from Rink resin, acylation with 4-bromomethyl-3-nitrobenzoic acid and amination with primary amines, reduction with tin chloride and cyclization, the desired 3,4-dihydro-2(1H)
1-Phenyl-4(1H)-quinazolinones and 2,3-Dihydro-1-phenyl-4(1H)quinazolinones as Potential Cholecystokinin Receptor Ligands. -With a view to their potentially interesting pharmacological activities the title compounds such as (VI), (IX), and (XI) are prepared. These structures show a good overlap in a