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The Synthesis of 2′,3′-Dideoxyadenosine from 2′-Deoxyadenosine

✍ Scribed by Robins, Morris J.; Robins, Roland K.


Book ID
126106439
Publisher
American Chemical Society
Year
1964
Tongue
English
Weight
275 KB
Volume
86
Category
Article
ISSN
0002-7863

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Synthesis of 3-Deaza-2′-deoxyadenosine a
✍ Frank Seela; Helmut Rosemeyer; Sabine Fischer 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 German ⚖ 589 KB

## Abstract The convergent syntheses of 3‐deazapurine 2′‐deoxy‐β‐D‐ribonucleosides and 2′,3′‐dideoxy‐D‐ribonucleosides, including 3‐deaza‐2′‐deoxyadenosine (1a) and 3‐deaza‐2′,3′‐dideoxyadenosine (1b) is described. The 4‐chloro‐l__H__‐imidazo[4,5‐c]pyridinyl anion derived from 5 was reacted with ei