Purine Nucleosides. XII. The Preparation of 2',3'-Dideoxyadenosine, 2',5'-Dideoxyadenosine, and 2',3',5'-Trideoxyadenosine from 2'-Deoxyadenosine *
✍ Scribed by Robins, Morris J.; McCarthy, James R.; Robins, Roland K.
- Book ID
- 126574401
- Publisher
- American Chemical Society
- Year
- 1966
- Tongue
- English
- Weight
- 810 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0006-2960
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## Abstract 2′,3′‐Dideoxyinosine‐^13^C~5~ (ddI‐^13^C~5~) and the related 2′,3′‐dideoxyadenosine‐^13^C~5~ (ddA‐^13^C~5~) were prepared from (S)‐5‐[^13^C~5~]2,3‐dideoxyribonolactone 1. From a batch of this starting material ddI‐^13^C~5~ was made in 27% overall yield in seven steps and ddA‐^13^C~5~ in