## Abstract α‐Deuterated tryptophan was prepared either by exchange of the α‐hydrogen of tryptophan or by hydrolysis and decarboxylation of ethyl 2‐formamido‐2‐carbethoxy‐3‐indole propionate, followed by treatment with CH~3~COO^2^H. α,β‐Dideuterated tryptophan was in turn synthetized from ethyl‐α‐a
The synthesis of [2-3H2] taurine and [2-3H2] hypotarine
✍ Scribed by J. H. Fellman
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 146 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
The synthesis of [2‐^3^H~2~]‐2‐aminoethanesulfonate [2‐^3^H]‐taurine by the reduction of cyanomethanesulfonic acid with tritium gas is described. The conversion of [2‐^3^H]‐taurine and its ^14^C and ^35^S isotopic forms to 2‐aminoethanesulfinate (hypotaurine) was accomplished by converting taurine to its corresponding sulfonyl chloride and reducing the latter with metallic zinc.
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