𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis of [2-3H2] taurine and [2-3H2] hypotarine

✍ Scribed by J. H. Fellman


Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
146 KB
Volume
18
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

The synthesis of [2‐^3^H~2~]‐2‐aminoethanesulfonate [2‐^3^H]‐taurine by the reduction of cyanomethanesulfonic acid with tritium gas is described. The conversion of [2‐^3^H]‐taurine and its ^14^C and ^35^S isotopic forms to 2‐aminoethanesulfinate (hypotaurine) was accomplished by converting taurine to its corresponding sulfonyl chloride and reducing the latter with metallic zinc.


📜 SIMILAR VOLUMES


Synthesis of (2R,S)- [2-2H] and [2,3-2H]
✍ Enzo Santaniello; Manuela Ravasi; Franca Astori 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 278 KB

## Abstract α‐Deuterated tryptophan was prepared either by exchange of the α‐hydrogen of tryptophan or by hydrolysis and decarboxylation of ethyl 2‐formamido‐2‐carbethoxy‐3‐indole propionate, followed by treatment with CH~3~COO^2^H. α,β‐Dideuterated tryptophan was in turn synthetized from ethyl‐α‐a

Synthesis of Z- and E-[2,3-2H2] and [2,3
✍ Billy W. Day; Sastry S. Jonnalagadda 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 338 KB

## Abstract ^2^H and ^3^H labeled __Z__‐ and __E__‐1,1‐dichloro‐2,3‐diphenylcyclopropane (1 and 2) were synthesized starting from NaB^2^H~4~ and NaB^3^H~4~ reduction of benzil. The resulting glycols were transformed to the 1,2‐labeled Z‐ and E‐stilbenes by thermolysis of their cyclic thionocarbonat

A convenient synthesis of 2S, 3S-[3-2H]-
✍ Lawrence Slieker; Stephen J. Benkovic 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 380 KB

Both 2S,3R-[2,3-2H2]-serine 5 and 2S,3S-[3-2H]-serine 6 have been pre ared from (E)-methyl-[2,3-2H2]-acrylate and (Z)-ethyl-[3-qH]-acrylate, respectively. The acrylate esters were converted to a mixture of isomeric bromohydrins by treatment with N-bromoacetamide. The ratio of 2-bromo-3-hydroxy speci

Synthesis of malondialdehyde-1-2H and ma
✍ Ashis K. Basu; Lawrence J. Marnett 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 215 KB

Two synthetic routes for deuterium labelling of 1,1,3,3-tetraethoxypropane, the precursor of the ubiquitous natural compound malondialdehyde, are described. In one scheme, deuterium is inc.orporated in ethyl vin 1 ether by metalation ing with $,,,. The conversion of the deuterated ether to monodeute

Synthesis of 2-furanylmethyl-α-2H and -3
✍ W. L. Nelson; P. J. Wirth; C. J. Bettis; L. A. Spitznagle 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 165 KB

## Abstract Synthesis of furosemide. specifically labelled at the 2‐furanylmethyl α‐position with ^2^H or ^3^H is reported. This synthesis required reduction of N‐[(2‐furanyhethyl)amino]‐4‐chloro‐5‐(N‐acetylaminosulfonyl)benzoia acid (2) with sodium ^2^H‐ or ^3^H‐borohydride. followed by alkaline h

Synthesis, 1H-NMR and mass spectra of 2-
✍ David G. Hine; Yasuyuki Ikeda; Kay Tanaka 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 437 KB

## Abstract 2‐^2^H, 2,3‐^2^H~2~ and 2,2‐^2^H~2~ ‐ short chain carboxylic acids were synthesized. Monodeuteration at the 2‐position of the carboxylic acids was achieved via decarboxylation of the corresponding carboxyldeuterated 2‐alkylmalonic acids. 2,3‐Dideuteration was achieved via catalytic deut