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The Synthesis of 1,1,2-Trimethyl-5,6-methylenedioxyindane from Safrole

✍ Scribed by Orcutt, Ruby Murray; Bogert, Marston Taylor


Book ID
127105831
Publisher
American Chemical Society
Year
1936
Tongue
English
Weight
340 KB
Volume
58
Category
Article
ISSN
0002-7863

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Synthesis of 5-alkynyl-2,2,6-trimethyl-1
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Herein we report an approach to the formation of 5-alkynyl-1,3-dioxin-4-ones using Suzuki-Miyaura cross-coupling reaction of potassium alkynyltrifluoroborate salts with 2,2,6-trimethyl-5-iodo-1,3dioxin-4-one. The resulting 5-ethynyltrimethylsilyl-1,3-dioxin-4-ones obtained through the Sonogashira re