The synthesis, bioactivity and enzyme stability of D-Ala2, ∇EPhe4,Leu5-enkephalins
✍ Scribed by Hitoshi Kimura; Charles H. Stammer; Yasuyuki Shimohigashi; Cui Ren-Lin; John Stewart
- Book ID
- 115756673
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 203 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
D-Ma2, D-Leu51Enkephalin (DADLE) labelled with tritium in the 2,6-positions of N-terminus tyrosine residue has been prepared. Synthesis of the precursor peptide, [2,6-dibromo-Tyrl]DADLE, was performed by solid phase synthesis using F'moc strategy. The peptide was tritiated catalytically to yield [2
## Abstract As a study preliminary to attempts at photoaffinity and cooperative affinity labelling of cells and cell membrane vesicles bearing opiate receptors, the title compounds were prepared and tested by rat brain membrane binding assays and by a modified guinea‐pig ileum bio‐assay. The potenc