The reaction of metallated Z-methyl (A) and E-benzyl e) dihydro-1,3-oxazines with electrophilic reagents (e.g. n-amyl iodide) producing alkylated derivatives (j and 2) which ultimately lead to aldehydes Q and 8) has been recently reported. 2 However, when the 2-
โฆ LIBER โฆ
The synthesis and rearrangement of 1,3-oxazines
โ Scribed by R.N. Warrener; E.N. Cain
- Publisher
- Elsevier Science
- Year
- 1966
- Tongue
- French
- Weight
- 179 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0040-4039
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## Abstract For Abstract see ChemInform Abstract in Full Text.
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## Abstract magnified image Alicyclic __N__โsubstituted 1,3โamino alcohols **13โ18** were prepared in a facile way in a oneโpot procedure from 1,3โoxazines **5โ8** in the presence of a ketone **9โ12**. The complex reaction involves palladiumโcatalyzed reduction, debenzylation and/or transimination