This accounts for 22 carbons and 23 protons. The three missing protons belong to 3 hydroxyl groups, which was confirmed by acetylation of 1 to form a triacetate [3, m/z 528 (M+)].
The structures of antibiotics YL-704 A and B
β Scribed by M. Suzuki; I. Takamori; A. Kinumaki; Y. Sugawara; T. Okuda
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- French
- Weight
- 187 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
In our screening studlee for new antibiotics produced by streptomycetes, a new eerie6 of basic macrollde complex, numbered YL-704, was leolated from the solvent extract of the culture filtrate of Streptomyces vlatensis var. sp. MCRL 0388. Isolated YL-704 complex was constituted by several antiblotlce and the structures of major two components (YL-704 A and B) were clearly determined.
The propertl.es of two antibiotics Were as followe: n-704 A (I),
π SIMILAR VOLUMES
Previous letters' have established the molecular formula of butirosins A (Ia) and B (Ib) as C21H41Ns01.s and have shown that three of the structural units, (S)-(-)-4-amino-Z-hydroxybutyric acid (II), neosamine C (2,6-diamino-2,6-dideoxy-D-glucose) (III), and a pentose (Dxylose (IVa) in Ia, D-ribose
Krivoruchko. -Chem. Abst. 1\_1. 50409 (1969). 9) The C-H long range couplings observed between C-4a (681.6) and 6-H (66.89) and between C-3 (675.3) and 3-CH3 (61.24) indicates that the remaining quaternary oxycarbon (680.2) is assignable to C-12b.