The structure-activity relationship of inhibitors of serotonin uptake and receptor binding

✍ Scribed by Corwin Hansch; Jonathan Caldwell

• Book ID: 104631799
• Publisher: Springer Netherlands
• Year: 1991
• Tongue: English
• Weight: 740 KB
• Volume: 5
• Category: Article
• ISSN: 0920-654X
• DOI: 10.1007/bf00125664

✦ Synopsis

An analysis of five different datasets of inhibitors of serotonin uptake has yielded quantitative structure/ activity relationships (QSARs) which delineate the role of steric and hydrophobic properties essential for inhibition by phenylethylamine-type analogues.