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Computer-assisted investigation of structure-activity relationships in serotonin-uptake blockers

✍ Scribed by L G Humber; D Lee; S Rakhit; A M Treasurywala

Book ID
103637473
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
750 KB
Volume
3
Category
Article
ISSN
0263-7855

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An analysis of five different datasets of inhibitors of serotonin uptake has yielded quantitative structure/ activity relationships (QSARs) which delineate the role of steric and hydrophobic properties essential for inhibition by phenylethylamine-type analogues.