𝔖 Bobbio Scriptorium
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The stereochemistry of antibiotics of the aureolic acid group

✍ Scribed by Yu.A. Berlin; M.N. Kolosov; L.A. Piotrovich

Book ID
104248820
Publisher
Elsevier Science
Year
1970
Tongue
French
Weight
159 KB
Volume
11
Category
Article
ISSN
0040-4039

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✦ Synopsis

AURROLIC acid (mithramycin, LA-7M7), chromomycins (aburamycins) end olivolqycins (NSC A-649) comprise a single group of anti-tuawur antibiotics of

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Biosynthetic studies on mithramycin (1, aureolic acid) using to a great extent modern genetic methods revealed several novel aspects of the biosynthesis of this class of antitumor agent. It could be proven that the aglycon moiety of the aureolic acids is constructed by a type II polyketide synthase

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