Five new HIDA-compounds were synthesized, labelled with 99mTc and compared with 99mTc-(2,6-dimethyl)HIDA viz. (N-2,6-dimethylphenylcarbamoylmethyl)iminodiacetic acid by means of TLC and biodistribution studies on rabbits. The computerized method used by Britton and Brown during renal studies was suc
The stability of99mTc-DTPA and99mTc-HIDA following ultrasonic nebulisation
β Scribed by N. Durovic; M. Pillay; P. H. Cox
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 182 KB
- Volume
- 14-14
- Category
- Article
- ISSN
- 0340-6997
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β¦ Synopsis
The stability of 99mTc-DTPA (diethylenetriamine-pentaacetic acid) and 99mTc-HIDA (2,6-diethylacetanilido-iminodiacetic acid) were evaluated following ultrasonic nebulisation. The results confirm that either of these radiopharmaceuticals can be used in our nebuliser without significant radiochemical breakdown.
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This report studies the binding rate of the radiopharmaceuticals 99mTc-DTPA, 99mTc-EDTA and 99mTc-DMSA to plasmatic proteins. The proteins bind to the tested radiopharmaceuticals in the following sequence: 99mTc-DTPA less than 99mTc-DMSA(C1) less than 99mTc-EDTA less than 99mTc-DMSA(C2) where C1 and