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Synthesis of five new99mTc-HIDA isomers and comparison with99mTc-HIDA

✍ Scribed by A. J. Wyk; P. J. Fourie; W. H. Zyl; M. G. Lötter; P. C. Minnaar


Publisher
Springer
Year
1979
Tongue
English
Weight
294 KB
Volume
4
Category
Article
ISSN
0340-6997

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✦ Synopsis


Five new HIDA-compounds were synthesized, labelled with 99mTc and compared with 99mTc-(2,6-dimethyl)HIDA viz. (N-2,6-dimethylphenylcarbamoylmethyl)iminodiacetic acid by means of TLC and biodistribution studies on rabbits. The computerized method used by Britton and Brown during renal studies was successfully adapted to study the biodistribution of these agents.


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