The specific effects of prior opioid exposure on placebo analgesia and placebo respiratory depression
โ Scribed by Fabrizio Benedetti; Martina Amanzio; Sergio Baldi; Caterina Casadio; Antonio Cavallo; Maurizio Mancuso; Enrico Ruffini; Alberto Oliaro; Giuliano Maggi
- Book ID
- 117479992
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 193 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0304-3959
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The analgesic effect of morphine in a mouse writhing assay was enhanced by the simultaneous administration of fluoxetine, an inhibitor of serotonin uptake. Fluoxetine reduced the ED, for morphine and extended the duration of morphine analgesia. The potentiation of morphine analgesia was particularly