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The single cell origin of normal granulocyte colonies in vitro

✍ Scribed by Michael Paran; Leo Sachs

Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
153 KB
Volume
73
Category
Article
ISSN
0021-9541

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✦ Synopsis

It has been shown by re-cloning of colonies formed in vitro from rat bone marrow cells, that normal granulocyte colonies can originate from single cells. No mixed macrophage (M) and granulocyte ( G ) colonies were obtained after re-cloning either M or G colonies. The results indicate, that clones of normal granulocytes and macrophages can be obtained in vitro, and that the mixed primary M and G colonies formed after seeding hematopoietic cells from animals presumably originate from a mixture of M and G cells.

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