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The Significance of the Sequence of Initiating and Promoting Actions in the Process of Skin Carcinogenesis in the Mouse

โœ Scribed by Berenblum, I; Haran, Nechama

Book ID
109832706
Publisher
Nature Publishing Group
Year
1955
Tongue
English
Weight
405 KB
Volume
9
Category
Article
ISSN
0007-0920

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Comparative study of lung carcinogenesis
Comparative study of lung carcinogenesis, promoting action in leukaemogenesis and initiating action in skin tumorigenesis by urethane, hydrazine and related compounds
โœ S. S. Mirvish; Louise Chen; Nechama Haran-Ghera; I. Berenblum ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 658 KB

Urefhane, N-hydroxyurefhane, hydrazine and sume related compounds were tested in C57BL/6 and S W R mice for activity as lung carcinogens, promoters of X-ray leukaemogenesis, and skin tumour initiators. Equimolar doses were used where possible. N-hydroxyurethane (ethyl hydroxycarbamate) was as strong