## D-Shikimic acids I-I4C, 6-14C and 7-(carboxyl) 14C have been biosyntheticaily prepared with specific activities of about 25 mCi/ mmole and with overall yields of 45% based on pyruvate 3,2 or I-1% as the respective starting materials. A crude cellfree homogenate of E. coli 83-24 was used to cat
The shikimate pathway: I. - Preparation of 3-3H, 4-3H and 2,4-3H2 D-shikimic acid
β Scribed by Dansette, P.; Azerad, R.
- Book ID
- 122917824
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- English
- Weight
- 555 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0300-9084
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## Abstract The four deuteriated 4βphenylbutyric [2,3β^2^H~2~]β, [4,4β^2^H~2~]β, [2,3,4,4β^2^H~4~]β, and [2,2,3,3,4,4β^2^H~6~]βacids have been synthesized in high isotopic purity by utilizing crossed Kolbe electrolysis of methyl hydrogen [^2^H~0~]β, [2,3β^2^H~2~], and [2,3,3,3β^2^H~4~]βsuccinates a
2 3 The preparation of 12,4-HI-and 12,4-HI-tomatidine was accomplished by oxydation of the unlabelled compoun to tomatidone, exchange of and direct reduction of the labelled tomatidone to tomatidine. The efficiency of the procedure was checked by physical (1H and 33C NMR, MS) methods.