The role of β-catenin in chronic myeloproliferative disorders
✍ Scribed by Monica P. Jauregui; Steven R. Sanchez; April A. Ewton; Lawrence Rice; Sherrie L. Perkins; Cherie H. Dunphy; Chung-Che Chang
- Book ID
- 116534517
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 486 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1532-8392
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Recent reports have suggested a previously unexpected variability in the expression of the dominant neoplastic clone in myeloproliferative disorders (MPD). We evaluated 49 female patients with MPD and informative at the X-linked androgen receptor (AR) locus to establish the X chromosome inactivation
## Abstract Familial chronic myeloproliferative disorders are defined when in the same pedigree at least two relatives have a chronic myeloproliferative disorder (CMD) as polycythemia vera (PV), essential thrombocythemia (ET) or primary myelofibrosis (PMF). This condition should be distinguished fr