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Pathogenetic Role of JAK2 V617F Mutation in Chronic Myeloproliferative Disorders

โœ Scribed by Hui-Chi Hsu


Book ID
118653956
Publisher
Elsevier Science
Year
2007
Tongue
Chinese
Weight
94 KB
Volume
70
Category
Article
ISSN
1726-4901

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โœ Melanie J Percy; Mary Frances McMullin ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 70 KB

## Abstract The discovery this year of a single mutation in the Janus Kinase (__JAK__)โ€2 gene in a high percentage of cases of polycythaemia vera (PV), essential thrombocythaemia (ET) and myelofibrosis suggests that it maybe the underlying molecular mechanism for these disorders. Different approach