The role of transcortin in glucocorticoid mediated enzyme induction: Tyrosine aminotransferase induction in hepatoma tissue culture cells
โ Scribed by Marc Lippman; E.Brad Thompson
- Book ID
- 118924546
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 552 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0022-4731
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๐ SIMILAR VOLUMES
## Abstract The increase in tyrosine aminotransferase activity which occurs in rat hepatoma tissue culture (HTC) cells in response to cyclic AMP analogs has been shown to be an enzyme induction, similar to the larger response observed in certain other hepatoma cells and in liver. A specific antibod
## Abstract Theophylline, a cyclic nucleotide phosphodiesterase inhibitor, increases the rate of tyrosine aminotransferase (TAT) degradation in rat hepatoma tissue culture (HTC) cells. Theophylline (0.1โ10 mM) causes a twoโ to fiveโfold increase in intracellular cAMP concentration but a 30โ60% decr