The Role of Thermogenesis in Antipsychotic Drug-induced Weight Gain
β Scribed by Aneta Stefanidis; Aaron N.A. Verty; Andrew M. Allen; Neil C. Owens; Michael A. Cowley; Brian J. Oldfield
- Book ID
- 109969359
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 506 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1930-7381
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π SIMILAR VOLUMES
Atypical antipsychotics (AP) have high affinity for many neurotransmitter receptors. Among these receptors, APs are antagonist at Ξ±βadrenergic and Ξ²βadrenergic receptors, and this pharmacological property has been postulated to be involved in the mechanism of action of these drugs with respect to bo
## Abstract ## Objectives Weight gain is an important side effect of antipsychotic (AP) treatment. Weight is regulated by multiple systems, including leptin, neuropeptide Y (NPY) and gonadal steroids. The aim was to investigate whether APβinduced weight gain was related to leptin and NPY abnormali