Management of atypical antipsychotic-induced weight gain in schizophrenic patients with topiramate
β Scribed by YI-HSIUNG LIN; CHIA-YIH LIU; MEI-CHUN HSIAO
- Book ID
- 108961897
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 39 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1323-1316
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## Abstract ## Objective Atypical antipsychotic drugs, in particular clozapine and olanzapine, influence cellular lipogenesis and are associated with metabolic side effects including weight gain. Insulin induced gene 2 (INSIG2) mediates feedback control of lipid synthesis and polymorphisms in the
## Abstract ## Objective The extent of weight changes in depressed patients who use atypical antipsychotics (AAP) as augmentation could not be easily predicted due to weight related symptoms of depression and the interaction with antidepressants which have weight reducing effects. ## Methods Pat