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Candidate gene studies of antipsychotic drug efficacy and drug-induced weight gain

✍ Scribed by Anil K. Malhotra

Book ID
105699155
Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
99 KB
Volume
6
Category
Article
ISSN
1029-8428

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## Abstract ## Objective Atypical antipsychotic drugs, in particular clozapine and olanzapine, influence cellular lipogenesis and are associated with metabolic side effects including weight gain. Insulin induced gene 2 (INSIG2) mediates feedback control of lipid synthesis and polymorphisms in the