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The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders

✍ Scribed by Kenny K.K Chung; Valina L Dawson; Ted M Dawson

Book ID
117343556
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
110 KB
Volume
24
Category
Article
ISSN
0166-2236

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## Abstract The ubiquitin proteasome system is a potent regulatory mechanism used to control protein stability in numerous cellular processes, including neural development. Many neurodegenerative diseases are featured by the accumulation of UPS‐associated proteins, suggesting the UPS dysfunction ma