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The role of the Bcl-2 family of apoptosis regulatory proteins in the immune system

✍ Scribed by Christine J. Hawkins; David L. Vaux


Book ID
115647854
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
103 KB
Volume
9
Category
Article
ISSN
1044-5323

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## Abstract Bcl‐2 family members are the arbiters of mitochondrial apoptotic pathway, which is conserved through evolution. The stoichiometry of pro‐ versus antiapoptotic Bcl‐2 family members in the cell determines whether the cell lives or dies. This fine balance is regulated at the transcriptiona