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The Role of T-Cell Receptor β Chain Genes in the Susceptibility to Rheumatoid Arthritis

✍ Scribed by MICHAEL McDERMOTT; DANIEL L. KASTNER; JOHN D. HOLLOMAN; GABRIELE SCHMIDT-WOLF; ANTE S. LUNDBERG; ANIMESH A. SINHA; CHRISTINE HSU; PATRICK CASHIN; MICHAEL G. MOLLOY; BRIAN MULCAHY; FERGUS SHANAHAN; FERGAL O'GARA; FIONA J. McCONNELL; CLAIRE ADAMS; MUHAMMAD A. KHAN; FREDERICK WOLFE; LAURENCE A. RUBIN; DANIEL O. CLEGG; DEE HUSEBYE; CHRISTOPHER I. AMOS; RYK H. WARD; AND HUGH O. McDEVITT


Book ID
119872361
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
214 KB
Volume
756
Category
Article
ISSN
0890-6564

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## Objective: To study the genes in the mouse background which predispose to the development of collagen-induced arthritis (cia). ## Methods: T cell receptor beta transgenic (tcrbetal) mice that have a t cell repertoire that predisposes to the development of cia were used. classic genetic studies