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The role of opioid mechanisms in the anorectic effects of stimulants: U50,488H enhances amphetamine inhibition of free feeding in rats

✍ Scribed by Paolo Nencini; Pacifico Valeri

Book ID
113226426
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
532 KB
Volume
48
Category
Article
ISSN
0091-3057

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✍ Masuo Ohno; Tsuneyuki Yamamoto; Hiroaki Araki; Showa Ueki πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 483 KB

The effect of a selective kappa-opioid agonist, U-50, 488H, on wet-dog shaking (WDS) induced by hippocampal stimulation was investigated and compared with that produced by morphine. U-50, 488H, as well as morphine, inhibited the appearance of WDS in a dose-dependent manner. U-50, 488H was approximat