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The role of opioid mechanisms in tolerance to behavioral effects of amphetamine

โœ Scribed by Paolo Nencini


Book ID
114075685
Publisher
Elsevier Science
Year
1988
Weight
66 KB
Volume
20
Category
Article
ISSN
0031-6989

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โœ Horace H. Loh; Pao-Luh Tao; Andrew P. Smith ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 862 KB

The molecular basis of opioid tolerance/dependence has long eluded researchers, but recent advances in receptor regulation have suggested a useful conceptual approach to the problem. In NG108-15 neuroblastoma x glioma hybrid (NG) cells, opioid agonists inhibit adenylate cyclase in a dose-dependent,