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The role of nicotinic receptors and calcium channels in mipafox induced inhibition of catecholamine release in bovine chromaffin cells

✍ Scribed by Luis M. Gutiérrez; Miguel A. Sogorb; Eugenio Vilanova; Salvador Viniegra

Book ID
116176367
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
696 KB
Volume
1
Category
Article
ISSN
1382-6689

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Differential inhibition of catecholamine
Differential inhibition of catecholamine secretion by amitriptyline through blockage of nicotinic receptors, sodium channels, and calcium channels in bovine adrenal chromaffin cells
✍ Tae-Ju Park; So-Young Shin; Byung-Chang Suh; Eun-Kyung Suh; Ihn-Soon Lee; Yong-S 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 2 views

We investigated the effects of amitriptyline, a tricyclic antidepressant, on [3H]norepinephrine ([3H]NE) secretion and ion flux in bovine adrenal chromaffin cells. Amitriptyline inhibited [3H]NE secretion induced by 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) and 70 mM K+. The half maximal inhib