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The role of mPGES-1 for prostaglandin E2production in primary human synovial cells

✍ Scribed by L Crofford, M Qian, A Sampey, V Lath, S Guo, M Peters-Golden…


Book ID
120708098
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
554 KB
Volume
5
Category
Article
ISSN
1478-6354

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Regulation of prostaglandin E2 synthase
✍ Antonio Carlos Pinheiro de Oliveira; Eduardo Candelario-Jalil; Harsharan S. Bhat 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 575 KB

## Abstract Prostaglandin E~2~ (PGE~2~) is among the most important mediators involved in neuroinflammatory processes. The final step of its synthesis is regulated by enzymes termed prostaglandin E~2~ synthases (PGES). Three PGES are known, cytosolic (c)PGES, membrane‐associated (m)PGES‐1 and mPGES