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Interleukin-1-Induced Prostaglandin E2 Biosynthesis in Human Synovial Cells Involves the Activation of Cytosolic Phospholipase A2 and Cyclooxygenase-2

✍ Scribed by Juana Angel; Francis Berenbaum; Corinne Le Denmat; Timo Nevalainen; Joëlle Masliah; Catherine Fournier


Book ID
115130594
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
893 KB
Volume
226
Category
Article
ISSN
1432-1327

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Basic calcium phosphate crystal–induced
✍ Maria P. Morgan; Linda C. Whelan; John D. Sallis; Conor J. McCarthy; Desmond J. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB 👁 2 views

## Abstract ## Objective To elucidate the mechanism of basic calcium phosphate (BCP) crystal–induced prostaglandin E~2~ (PGE~2~) production in human foreskin fibroblasts (HFFs), to identify the signaling pathway involved in the induction of cyclooxygenase 2 (COX‐2) messenger RNA (mRNA) by BCP crys