The role of molecular imaging in the development of dendritic cell-based cancer vaccines
โ Scribed by Giovanni Lucignani; Maria Rescigno
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 139 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0340-6997
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## Abstract Success of immunotherapy with dendritic cells (DC) to treat cancer is highly dependent on their interaction with and activation of antigen specific T cells. To maximize DCโT cell contact accurate delivery of the therapeutic cells into the lymph node, or efficient trafficking of DC to th
regarding such properties as the surface electrostatic potential and the physicochemical character of the antigen binding groove, both of which are pivotal in antigenic peptide affinity 8,9 . By contrast, few differences have been found between the molecular properties of HLA-DR alleles deemed susce