The role of dendritic cells in contact hypersensitivity

✍ Scribed by Maya Krasteva; Jeanne Kehren; Genevieve Choquet; Dominique Kaiserlian; Jean-Francois Nicolas

• Publisher: Elsevier Science
• Year: 1998
• Tongue: English
• Weight: 76 KB
• Volume: 19
• Category: Article
• ISSN: 0167-5699
• DOI: 10.1016/s0167-5699(98)01272-9

✦ Synopsis

regarding such properties as the surface electrostatic potential and the physicochemical character of the antigen binding groove, both of which are pivotal in antigenic peptide affinity 8,9 . By contrast, few differences have been found between the molecular properties of HLA-DR alleles deemed susceptible or resistant to type 1 diabetes 10 . This of course does not rule out differences in the regulatory regions of the DQAB genes, that apparently exist 9 but have yet to be linked to either differences in strength of expression, or susceptibility and resistance to type 1 diabetes.