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The role of CD4+ T cell help in cancer immunity and the formulation of novel cancer vaccines

โœ Scribed by Deepak P. Assudani; Roger B. V. Horton; Morgan G. Mathieu; Stephanie E. B. McArdle; Robert C. Rees

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
358 KB
Volume
56
Category
Article
ISSN
0340-7004

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โœ Drew M Pardoll; Suzanne L Topalian ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 630 KB

While most of the focus in cancer immunology is on CD8+ cytotoxic T lymphocyte responses, recent evidence indicates that CD4+ T cells are an equally critical component of the antitumor immune response. Successful immunity to cancer will therefore require activation of tumor-specific CD4+ T cells. Tu