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The role of mitochondria in cell death — Regulation of the pro-apoptotic protein Bak

✍ Scribed by Stojanovski, Diana; Lazarou, Michael; Ryan, Michael T.

Book ID: 122412424
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 58 KB
Volume: 1817
Category: Article
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2012.06.420

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## Abstract Apoptosis is a physiological mechanism allowing for the removal of abundant or potentially harmful cells. The hallmarks of apoptosis include degradation of cellular DNA, exposure of phosphatidylserine at the outer leaflet of the cell membrane and cell shrinkage. Phosphatidylserine expos