The Role of the Pro-Apoptotic Bcl-2 Family Member Bim in Physiological Cell Death
β Scribed by PHILIPPE BOUILLET; DAVID C.S. HUANG; LORRAINE A. O'REILLY; HAMSA PUTHALAKATH; LIAM O'CONNOR; SUZANNE CORY; JERRY M. ADAMS; ANDREAS STRASSER
- Book ID
- 111396199
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 53 KB
- Volume
- 926
- Category
- Article
- ISSN
- 0890-6564
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The anti-apoptotic members of the Bcl-2 family, such as Bcl-2 and Bcl-XL, play a central role in preventing the induction of apoptosis via the intrinsic apoptotic pathway. It has been previously shown that induction of apoptosis by the pro-apoptotic Bcl-2 family member Bok is not antagonized by eith
Samples of normal esophageal squamous epithelium (n β«Ψβ¬ 10), severe squamous cell dyplasia (n β«Ψβ¬ 22), carcinoma in situ (n β«Ψβ¬ 15), invasive squamous cell carcinoma (n β«Ψβ¬ 172), lymph-node metastasis (n β«Ψβ¬ 21) and 2 permanent esophageal squamous cell carcinoma cell lines were analyzed immunohistoc