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Mitochondria as the target of the pro-apoptotic protein Bax

✍ Scribed by Emine Er; Lisa Oliver; Pierre-François Cartron; Philippe Juin; Stephen Manon; François M. Vallette


Book ID
119193224
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
409 KB
Volume
1757
Category
Article
ISSN
0005-2728

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## Abstract Bax, a multi‐domain protein belonging to the large family of Bcl‐2 proteins, has a pivotal role for the initiation of the cytochrome __c__‐mediated apoptosis, a vital physiologic process to eliminate damaged or unwanted cells. In response to specific stimuli Bax translocates from cytoso