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Conformational changes and protein stability of the pro-apoptotic protein Bax

✍ Scribed by Stephanie Bleicken; Kornelius Zeth

Book ID
106402397
Publisher
Springer US
Year
2009
Tongue
English
Weight
609 KB
Volume
41
Category
Article
ISSN
0145-479X

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## Abstract Bax, a multi‐domain protein belonging to the large family of Bcl‐2 proteins, has a pivotal role for the initiation of the cytochrome __c__‐mediated apoptosis, a vital physiologic process to eliminate damaged or unwanted cells. In response to specific stimuli Bax translocates from cytoso