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Pro-apoptotic protein–protein interactions of the extended N-AChE terminus

✍ Scribed by Debra Toiber; David S. Greenberg; Hermona Soreq

Book ID
106207570
Publisher
Springer
Year
2009
Tongue
English
Weight
316 KB
Volume
116
Category
Article
ISSN
1435-1463

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## Abstract The ASPP proteins are apoptosis regulators: ASPP1 and ASPP2 promote, while iASPP inhibits, apoptosis. The mechanism by which these different outcomes are achieved is still unknown. The C‐terminal ankyrin repeats and SH3 domain (ANK‐SH3) mediate the interactions of the ASPP proteins with