## KYOICHI INOUE The depressant effect of interferon beta on drugmetabolizing activity in the human liver was investigated. Seven patients with chronic hepatitis C were treated with interferon beta at doses of 3 x 10' to 9 x 10' IU/day for 8 wk. The activities of 7-methoxycoumarin O-demethylase an
The role of lymphocytes, macrophages and interferon in the depression of drug metabolism by dextran sulfate
β Scribed by Theresa C. Peterson; Kenneth W. Renton
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 594 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0162-3109
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The depressant effect of interferon-alpha on drug metabolizing activity in the liver has been investigated in 12 patients with chronic active hepatitis B. 7-methoxy-coumarin (7-MC) O-demethylase and 7-ethoxycoumarin (7-EC) O-deethylase, in specimens obtained by liver biopsy, were measured before and
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