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The role of irf-1 and caspase-7 in ifn-gamma enhancement ofFAS-mediated apoptosis in achn renal cell carcinoma cells

✍ Scribed by Y. Tomita; V. Bilim; N. Hara; T. Kasahara; K. Takahashi


Book ID
117658303
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
180 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Abstract Caspases exist as zymogens, and are activated by various extracellular stimuli, leading to apoptosis. One such stimulus is Fas/CD95, a member of the tumor necrosis factor receptor family, providing one means of cytotoxic T lymphocyte (CTL)‐mediated cell lysis. Clinical evidence has show