Role of IRF-1 and caspase-7 in IFN-γ enh
✍
Yoshihiko Tomita; Vladimir Bilim; Noboru Hara; Takashi Kasahara; Kota Takahashi
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
French
⚖ 701 KB
## Abstract Caspases exist as zymogens, and are activated by various extracellular stimuli, leading to apoptosis. One such stimulus is Fas/CD95, a member of the tumor necrosis factor receptor family, providing one means of cytotoxic T lymphocyte (CTL)‐mediated cell lysis. Clinical evidence has show