Role of drug metabolism in drug discover
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Gondi N. Kumar; Sekhar Surapaneni
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Article
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2001
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John Wiley and Sons
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English
โ 300 KB
๐ 1 views
## Abstract Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. High metabolic lability usually leads to poor bioavailability and high clearance. Formation of active or toxic metabolites will have an impact on the pharmacological and t