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The Role of DPNASE in The Mechanism of Action of an Antitumor Alkylating Agent on Ehrlich Ascites Cells

โœ Scribed by Ernest Kun, B. Langer, B. Ulrich, Helmut Holzer and H. Grunicke


Book ID
123657981
Publisher
National Academy of Sciences
Year
1964
Tongue
English
Weight
281 KB
Volume
52
Category
Article
ISSN
0027-8424

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Antitumor agents LII: The effects of mol
โœ Iris H. Hall; Y. F. Liou; K. H. Lee ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 551 KB

o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites