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Comparative effects of biologically active alkylating agents on the viability of Ehrlich-Lettre ascites cells

✍ Scribed by J. N. Ahuja; Laura Martinez; L. S. Dietrich

Book ID
104846060
Publisher
Springer
Year
1964
Tongue
English
Weight
414 KB
Volume
51
Category
Article
ISSN
0028-1042

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o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites