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The Role of DNA Ploidy in the Differentiation of WEHI-3B D- Leukemia Cells Transfected with the Granulocyte Colony-Stimulating Factor Receptor Gene

✍ Scribed by Jianming Li; Debbie C. Koay; Alan C. Sartorelli

Book ID
115602127
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
815 KB
Volume
219
Category
Article
ISSN
0014-4827

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Granulocytic colony-stimulating factor (
Granulocytic colony-stimulating factor (G-CSF) does not induce differentiation of WEHI3B(D+) cells but is required for the survival of the mature progeny
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It has been reported previously that cells of the murine myelomonocytic leukaemia cell line WEH13B(D+) can be induced to differentiate into mature monocytes by incubation with post-endotoxin serum (ES), granulocyte-colony-stimulating factor (G-CSF) or actinomycin D (AMD). We have investigated the ki